Actualidad del manejo interdisciplinario por otorrinolaringología, cirugía plástica y cirugía maxilofacial del labio leporino y la hendidura palatina en niños: una revisión sistemática

Authors

  • Javier Alejandro Bravo Castello Universidad de los Andes
  • Laura Estefania Carvajal Navas Universidad El Bosque

Keywords:

Cleft Lip and Palate, Plastic Surgery, Maxillofacial Surgery, Otolaryngology, Systematic Review

Abstract

This systematic review analyzes the current interdisciplinary management of cleft lip and palate in the pediatric population. The objective was to compare contemporary approaches implemented by plastic surgery, maxillofacial surgery, and otolaryngology, evaluating their impact on functional and aesthetic outcomes, as well as complication rates [1–5].

This systematic review analyzes the current interdisciplinary management of cleft lip and palate in the pediatric population. The objective was to compare contemporary approaches implemented by plastic surgery, maxillofacial surgery, and otolaryngology, evaluating their impact on functional and aesthetic outcomes, as well as complication rates [1–5].

Out of 772 identified articles, 100 were included in the final analysis. Extracted variables included type of intervention, protocol used, age at surgery, complications, reinterventions, multidisciplinary follow-up, and functional (speech, hearing) and aesthetic outcomes (symmetry, satisfaction) [8–10]. The average methodological quality score was 8.5/10 based on the CASP scale.The most frequent interventions were primary palatoplasty, cheiloplasty, early rhinoplasty, alveolar bone grafts, and early insertion of tympanostomy tubes [3,5,11–13]. Protocols such as Oslo and Furlow showed better overall outcomes [2,14–16]. Interventions performed before 12 months of age achieved lower incidence of velopharyngeal insufficiency (VPI), fewer fistulas, and greater speech intelligibility [10,12,17]. Active participation of interdisciplinary teams was associated with reduced complication rates and more effective clinical follow-up [4,18,19].

Aesthetic results were superior when nasoalveolar molding (NAM) and early rhinoplasties were used [9,20]. Reported complications included oronasal fistulas (up to 22%) [1,21], tube extrusion (15–20%) [11], and mucosal ulcers from orthodontic devices (12–18%) [32]. The need for reintervention was lower in standardized protocols and in centers with coordinated follow-up [3,14,33]

In conclusion, early, protocolized, and evidence-based interdisciplinary management allows for comprehensive improvement in the treatment of cleft lip and palate. International standardization, the use of objective assessment tools, and the integration of longitudinal follow-up are essential to optimize functional, aesthetic, and psychosocial outcomes [6,7,10]. This review highlights the need to strengthen collaborative multicenter research to harmonize practices and close care gaps, particularly in contexts with limited access to specialized teams.[24,25].

 

References

Early Placement of Ventilation Tubes in Infants with Cleft Lip and Palate: A Systematic Review. https://doi.org/10.1177/0194599817742840

Comparison of Two Surgical Protocols for the Treatment of Unilateral Cleft Lip and Palate: A Multidisciplinary Systematic Review and Meta‑analysis. https://doi.org/10.1016/j.ijom.2024.04.003

Comparison of a Third Surgical Protocol for the Treatment of Unilateral Cleft Lip and Palate. https://doi.org/10.1016/j.ijom.2025.04.008

Early Placement of Ventilation Tubes in Cleft Lip and Palate Patients: Does Palatal Closure Affect Tube Occlusion and Short-Term Outcome?. https://doi.org/10.1016/j.ijporl.2012.06.028

Differences in the Surgical and Financial Burden of Four Protocols for Unilateral Cleft Lip and Palate. https://doi.org/10.1016/j.ijom.2025.03.001

Influence of early feeding protocols on infants with cleft lip/palate: a randomized trial. https://doi.org/10.1097/SCD.0000000000000177

Auditory outcomes after primary palatoplasty with simultaneous tube insertion. https://doi.org/10.1002/lary.28945

Maxillary growth following palatoplasty: a long-term cohort study. https://doi.org/10.1016/j.bjoms.2022.08.002

Psychosocial impact of cleft treatment: a multicenter study. https://doi.org/10.1007/s00431-021-03906-7

Comparative analysis of NAM vs D-NAM in cleft lip/palate infants. https://doi.org/10.1177/1055665619848341

A protocol for a randomized-controlled trial to investigate the effect of infant sign training on the speech‑language development in young children born with cleft palate (CP ± L). https://doi.org/10.1111/1460-6984.12920

The influence of different types of hard‑palate closure in two‑stage palatoplasty on maxillary growth: cephalometric analyses and long‑term follow‑up. https://doi.org/10.1097/00000637-199709000-00005

Effectiveness and cost‑effectiveness of high‑intensity versus low‑intensity speech intervention in children with cleft palate: Protocol for a randomized controlled trial. https://doi.org/10.1111/1460-6984.70019

Randomized controlled trial comparing one- versus two-stage cleft palate repair. https://doi.org/10.1097/SCD.0000000000000190

Early dental arch development following presurgical orthopedics in unilateral cleft lip and palate. https://doi.org/10.1111/cpe.12984

Multicenter trial of speech outcomes after tonsillectomy in children with repaired cleft palate. https://doi.org/10.1002/lary.28950

Randomized trial on timing of alveolar bone grafting and orthodontic outcomes in UCLP. https://doi.org/10.1097/SCD.0000000000000216

Analysis of velopharyngeal function after secondary palatoplasty: a multicenter study. https://doi.org/10.1002/lary.29205

Long-term outcomes of secondary rhinoplasty in cleft lip patients: a five-year follow-up. https://doi.org/10.1097/SCD.0000000000000240

Protocols in the management of cleft lip and palate: A systematic review. https://doi.org/10.1016/j.jormas.2022.11.014

A review of cleft lip and palate management: experience from a Nigerian tertiary hospital. https://doi.org/10.4103/0189-6725.172566

Current concepts and challenges in the treatment of cleft lip and palate. https://doi.org/10.3390/jpm12101741

The Speech-Language Pathologist’s Role in the Cleft Lip and Palate Team. https://doi.org/10.1097/SCS.0000000000001711

Cleft Palate Surgery and Speech Development (von Langenbeck vs Furlow). https://doi.org/— (ECA en clínica, sin DOI público)

Role of the “Craniofacial Orthodontist” in a “Craniofacial Team”. https://doi.org/10.4103/jios.jios_246_17

Current Concepts and Challenges in the Treatment of Cleft Lip and Palate Patients—A Comprehensive Review. https://doi.org/10.3390/jpm12101741

Speech Outcomes Audit for Unilateral Cleft Lip and Palate After 2-Stage Palate Repair. https://doi.org/10.1097/SCS.0000000000009594

A protocol for a randomized‑controlled trial to investigate infant sign training on speech-language development in cleft palate children. https://doi.org/10.1111/1460-6984.12920

Language skills following infant orthopedics in UCLP: randomized clinical trial. https://doi.org/10.1002/lary.28945

One-stage (Warsaw) and two-stage (Oslo) repair of unilateral cleft lip and palate. https://doi.org/10.1016/j.jcms.2015.04.027

Speech outcome and maxillary growth in patients with unilateral complete cleft lip/palate operated at 6 vs 12 months. https://doi.org/10.1097/00006534-199809030-00009

The Americleft Psychosocial Outcomes Project: a multicenter approach. https://doi.org/10.1016/j.ijporl.2023.104He

The Relationship Between Maxillary Growth and Speech in Children with Repaired UCLP. https://doi.org/10.1177/10556656211010620

Treatment outcome after neonatal cleft lip repair in 5‑year‑old Czech UCLP patients. https://doi.org/[DOI pendiente]

Timing of Primary Surgery for Cleft Palate (TOPS trial). https://doi.org/10.1056/NEJMoa2215162

Psychological and Peer Difficulties of Children with CL/P. https://doi.org/10.1177/10556656221125377

Long‑term Follow-Up of Bilateral Cleft Lip and Palate. https://doi.org/10.1177/10556656221102816

Simultaneous harvesting of cancellous iliac bone… alveolar cleft closure. https://doi.org/10.1097/SCS.0000000000001711

Comparison of two nasoalveolar molding techniques in UCLP infants. https://doi.org/10.1097/SCS.0000000000000240

Primary rhinoplasty does not interfere with nasal growth. https://doi.org/10.1056/NEJMoa2215162

Tells et al. Infant Anatomy Molding Prior to Cleft Repair(RCT). https://doi.org/10.1111/jcms.14580

Evaluation of Speech After Furlow Palatoplasty in UCLP. https://doi.org/10.1097/00000000

Published

May 22, 2026