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Adenosina desaminasa en el diagnóstico molecular de pacientes con pleuritis tuberculosa y su relación con la respuesta inmunológica

Authors

  • Erika Patricia Solano Fontalvo Universidad de Oriente Venezuela
  • Laura Vanesa Ríos Samper Universidad El Bosque
  • Xintia Raquel Sarmiento Parra Corporación Universitaria Rafael Núñez
  • Karen Lorena Mesa Cruz Universidad Antonio Nariño
  • Laura Camila Acosta Wilchez Universidad Nacional de Colombia
  • Francisco Javier Hernandez Ortega Universidad Cooperativa de Colombia - Pasto

Keywords:

Tuberculous pleuritis, pleural tuberculosis, tuberculous pleural effusion, adenosine deaminase, anergy.

Abstract

A systematic review was carried out, where it was evidenced an analysis about the
usefulness of adenosine deaminase from the interpretation of its cut-off points,
sensitivity, specificity and predictive values. In order to get to a relationship of
the contexts of pleural tuberculosis with the variation of adenosine deaminase
levels and anergy from a pathophysiology and immunological interpretation. For
an understanding of the role of this enzyme in the diagnosis and immunotherapy in
relation to Mycobacterium tuberculosis, where anergy is fundamental.

Published

May 5, 2022

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